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Research HighlightJanuary 05, 2024Investigating vaccine responses in older adults
Researchers at JAX and UConn Health are rigorously investigating why vaccines don’t work as well in some older adults. -
Blog PostFebruary 14, 2022Systemic Immune Responses - Humanized Mice
The Jackson Laboratory (JAX) has developed a versatile toolset of mouse models capable of supporting extensive functional components of the human immune system. These mice provide a preclinical research platform that yields sensitive, reproducible results to screen drug candidates for inflammatory responses. -
Blog PostJanuary 20, 2021Advancing Humanized NSG Mice for Immuno-Oncology Testing
Immunologically humanized NSGTM and its variant strains are a powerful system that facilitates cutting-edge in vivo preclinical testing of a wide range of immuno-oncology therapeutic candidates. -
Blog PostApril 21, 2020CD34+ Hematopoietic Stem Cell Humanized Mice: The Basics
Humanized mouse models serve as an innovative and cost-effective platform to simulate trials, evaluate multiple drugs alone or in combination, and produce predictive data. But, there are a number of questions that frequently arise with this model. Here are some of the more frequent questions and answers to using CD34+ hematopoietic stem cell humanized mice.
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Featured ArticleDecember 19, 2023Exploring immunological memory in natural killer cells
Silke Paust explores immunological memory in natural killer cells. Her work will change the way we view the immune system and equip it to defend against pathogens and disease. -
Research HighlightFebruary 01, 2021
Novel antibody tests reveal complexity of immune response to covid-19
The interaction of SARS-CoV-2, the novel coronavirus causing the global COVID-19 pandemic, and the human immune system has been the focus of intensive research. -
Blog PostJuly 21, 2020Why humanized mice?
If you read about biomedical breakthroughs, you are hearing more and more about “humanized” mice. But, what is a humanized mouse and why on earth would scientists want to experiment in this way? -
Press ReleaseJanuary 23, 2020Small molecules mean big data for health and disease
Jackson Laboratory (JAX) Associate Professor Shuzhao Li uses high-resolution mass spectrometers to quantify metabolism, measuring thousands of small molecules in the body.
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