The genetic background of a strain profoundly affects the phenotype and potential applications of a mouse model. JAX strains are carefully selected for scientific value and notable characteristics, and thoroughly curated to provide you with the knowledge you need to select the right model for your in vivo testing studies with confidence.
We provide a variety of tools and services for modeling etiology and studying immune responses. Our Preclinical Research Service offerings incorporate innovation, dependability, and a dedication to customer satisfaction to help you move from concept to IND faster.
JAX can work with you to collect IND-enabling data from your in vivo pharmacology studies. We offer multiple validated routes of administration combined with a variety of behavioral, molecular, in-life and postmortem assays.
Learn about the ways in which JAX can support your research in the areas of neurodegenerative, neuromuscular, and neurodevelopmental disorders. JAX offers tailored models and efficacy studies for your preclinical research.
Read MoreDiscover JAX's Oncology models and efficacy studies. Evaluate your CAR or Antibody based therapeutics using JAX's cutting-edge immune-humanized mice featuring characterized PDX tumors.
Read MoreAnalyze the human immune and tumor environment to assess the efficacy of your therapeutic through a safety or pharmacokinetic in vivo study using a mouse model with a humanized immune system.
Read MoreAssess therapeutic antibodies and compounds, which include preclinical studies on GvHD using immune humanized mouse models incorporating CD34+ and PBMC donors.
Read MoreConduct tailored efficacy studies for assessing new and established therapeutic compounds for various autoimmune disorders, including Lupus, Type 1 Diabetes, and Psoriasis.
Read MoreJAX offers the world's largest collection of spontaneous, targeted, and transgenic mutant mouse strains, hundreds of which model rare diseases, for preclinical research.
Read MoreSelecting the appropriate model is crucial for metabolic research. Discover the ideal model for your research needs from JAX's extensive selection of diabetes and obesity mouse models. Our collection includes a variety of NASH models and diet-induced models to enhance your in vivo study.
Read MoreOur FcRn models provide reliable data for expediting the development of therapeutic candidates for clinical trials. Our approach offers a viable and established option in place of using non-human primates. These in vivo studies can assess various therapeutic candidates containing Fc-domains or albumin.
Read MoreGain insight from JAX’s experience in vivarium operations, mouse genetics, breeding, husbandry, surgical techniques, and more. With an assessment of your specific preclinical research needs, JAX can provide guidance on recommended studies or institutional approaches, as well as support in their implementation.
Read MoreA glimpse at the wide range of platforms and services JAX offers to help move you from drug discovery to IND filing.
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