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Blog PostMarch 13, 2019Welcome MSNASH/PcoJ: the latest mouse model from JAX
Utilizing the most translationally-relevant in vivo model is crucial to generating meaningful data and getting a potential therapeutic closer to Investigational New Drug Application (IND) filing. With the availability of the MSNASH/PcoJ mouse from JAX, which can be used to study obesity, diabetes, and metabolic syndrome—including NASH, researchers worldwide can access and include this in vivo model that offers several benefits over the previously published models. -
Blog PostAugust 17, 2016Finding “DIAMONDS” in the rough – serendipity in research
An elegant clinicopathologic characterization of a Diet-Induced Animal Model of Non-alcoholic fatty liver Disease (DIAMOND) reminds us of a simple truth about how many discoveries are made: by paying attention and being prepared to recognize the value of an unexpected finding.
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Research HighlightMarch 31, 2017Research offers insights into FcRn-albumin interactions, liver protection
How FcRn interacts with albumin and determines its fate was previously unknown. -
JAX NotesApril 01, 2009
JAX Mice help reveal potential health benefits of resveratrol
Studies in mice suggest that resveratrol, a plant-derived compound, may be beneficial in treating or preventing a host of cardiovascular, metabolic, autoimmune and neurodegenerative diseases.
