| MODEL |
JAX # |
TYPE |
DESCRIPTION |
SOURCE |
| MAPT(H1.0)-GR |
35398 |
Genome replacement |
190kB human construct of H1 haplotype replacing mouse Mapt |
Koob |
| MAPT(H2.1)-GR |
33668 |
Genome replacement |
190kB human construct of H2 haplotype replacing mouse Mapt |
Koob |
| MAPT(H1.0*)P301L-GR |
37420 |
Genome replacement |
190kB human construct of H1 haplotype with P301L variant replacing mouse Mapt |
Koob |
| MAPT(H1.0*N279K)-GR |
35794 |
Genome replacement |
190kB human construct of H1 haplotype with N279K risk variant replacing mouse Mapt |
Koob |
| MAPT 10IVS+16 C>T |
36664 |
Genome replacement |
190kB human construct of H1 haplotype with non-coding C to T (rs63751011) mutation in intron 10 replacing mouse Mapt |
Koob |