Retinal degeneration 7 rd7

Retinal degeneration 7 (rd7)

Light microscopy shows retinal waves, whorls and rosettes that increase and decrease concordant with retinal spots and later on-set photoreceptor degeneration. A 380-nt deletion from the coding region of a photoreceptor-specific nuclear receptor gene, Pnr, causes retinal abnormalities in rd7 mice.