Gary Churchill, Ph.D.
Professor, Karl Gunnar Johansson Chair
Employs a systems approach to investigate the genetics of health and disease and complex disease-related traits in the mouse.
Our lab is actively applying a systems approach to study the genetics of health and disease, incorporating new statistical methods for the investigation of complex disease-related traits in the mouse. We employ a combination of strategies to investigate the genetic basis of these complex traits. We are developing new methods and software that will improve the power of quantitative trait loci mapping and microarray analysis, as well as graphical models that aim to intuitively and precisely characterize the genetic architecture of disease.
Within the Center for Genome Dynamics, we are part of a consortium of investigators with a shared interest in a holistic approach to understanding genetics from an evolutionary perspective. With an eye on the future of mouse genetics, we are also establishing two new mouse resources for complex trait analysis: the Collaborative Cross and the Diversity Outbred.
Education and experience
Education
University of Washington
Ph.D., biostatistics
1988
Massachusetts Institute of Technology
B.S., mathematics
1983
Experience
The Jackson Laboratory
Professor
2003
The Jackson Laboratory
Associate Professor
1998-2003
The Jackson Laboratory
Visiting Investigator
1997-1998
Cornell University
Associate Professor, Biometrics Unit
1996-1999
Cornell University
Assistant Professor, Biometrics Unit
1990-1996
University of Southern California
Visiting Assistant Professor, Department of Mathematics
1989-1990
University of Southern California
Research Associate, Department of Mathematics
1988-1989
Fred Hutchinson Cancer Research Center
Research Associate
1983-1986
Massachusetts Institute of Technology
Research Assistant, Department of Psychology
1981-1983
Grants, Honors, and Accomplishments
The Ellison Senior Scholar Award
2010
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Media ReleaseOctober 09, 2024Study probes how eating less can extend lifespan
Researchers at The Jackson Laboratory conduct pivotal study into aging and lifespan to uncover new details about how diets might make people live longer — but also their negative side effects -
Research HighlightJuly 19, 2023Identifying signature signs of aging-related decline
Gary Churchill and his team are working to identify signature signs of aging-related decline and have identified protein changes across ten tissue types that depend on age and sex. -
Research HighlightApril 11, 2023Churchill Lab performs multi-omics study on protein phosphorylation regulators
The Churchill lab performed an integrative multi-omics analysis of 58 genetically diverse Collaborative Cross strains to identify regulators of protein phosphorylation. -
Search MagazineApril 26, 2022Using machine learning to keep an eye on healthy function and disease
JAX scientist Vivek Kumar, Ph.D., is using machine learning to automate and improve analysis of mouse behavior and movement. The new methods have already yielded important biological insights, and they may have even more profound implications for research into human diseases such as ALS, Alzheimer’s disease, and even cancer.
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Press ReleaseOctober 25, 2023International Mammalian Genome Society recognizes JAX Scientists
Scientists from JAX are being recognized for their outstanding achievements by the IMGS, a group that fosters research in mammalian genetics, and represents its members in their professional activities. -
Research HighlightMay 09, 2023Variability in the earliest stages of development
The processes enabling pluripotency at the very beginning of life are more different between mouse strains than you might expect. -
Featured ArticleSeptember 06, 2022Connecting life-long dietary restrictions and loss of cognitive function
Andrew Ouellette is helping to discover new connections between life-long dietary restriction and the loss of cognitive function. -
Research HighlightOctober 06, 2021Exploring the complex regulation of protein abundance
Using advanced mouse populations and newly developed research protocols for measuring proteins, JAX researchers are exploring how proteome is regulated, why it varies on individual genetics, and how consistent this is across different populations.